TL;DR
- CIENCE = multichannel lead generation powerhouse with 200M+ contact database, machine-powered processes, and enterprise focus.
- Operatix = global sales acceleration firm with 300+ SDRs, multilingual capabilities across 20+ languages, and B2B software specialization.
- If you want a data-driven multichannel approach with sophisticated technology backing, CIENCE is your play.
- If you want a human-first global sales team with deep cultural understanding and multilingual reach, Operatix fits better.
- But if you want pure cold calling excellence, transparent pricing, and genuine human connection? There’s a sharper alternative: RemoteAides.
Why This Comparison Matters
The challenge of scaling outbound hasn’t changed. You’re still stuck between two hard choices: build an expensive in-house team or trust an outsourced partner with your brand reputation.
The problem is that most founders treat this decision like picking a vendor. They compare pricing sheets, read testimonials, and hope for the best. But here’s what they miss: your outbound partner doesn’t just represent your company. They ARE your company to every prospect they call.
CIENCE and Operatix are two names that consistently surface in these conversations, but they couldn’t be more different in how they approach outbound. CIENCE leans heavily on technology and data sophistication. Operatix focuses on human expertise with global cultural intelligence.
Both can theoretically get you meetings. In practice, the experience and the results depend entirely on which approach aligns better with how your prospects want to be reached.
CIENCE: Machine-Powered Multichannel at Scale
CIENCE helps companies grow through multi-channel prospecting, starting with highly accurate data from a 200M+ contact universe, then providing lead generation and outbound sales processes to produce qualified appointments. They position themselves as “human-driven and machine-powered,” which essentially means they use technology to optimize every part of the process while humans execute the conversations.
Their approach is methodical. They analyze your ICP, map out buying committees, create multichannel sequences that blend email, LinkedIn, and calls, then track every interaction to optimize performance. The system is designed for predictability and scale.
As an Inc. 5000 company ranked #8 fastest growing Marketing & Advertising company in the U.S., their team of 1200+ employees has successfully served hundreds of clients in more than 205 industries. The scale is undeniable.
The strength here is sophistication. CIENCE doesn’t just send cold emails or make random calls. They build comprehensive campaigns that touch prospects across multiple channels with coordinated messaging. For companies selling complex enterprise solutions where buying cycles are long and multiple stakeholders are involved, this orchestrated approach can be powerful.
The potential weakness is that with all this technology and process, the human element can sometimes feel secondary. Some reviews mention English language barriers creating issues in the copywriting process, with every grammatical error potentially losing 7% of prospects reading emails. When you’re paying premium prices for outbound, quality control becomes critical.
Why companies choose CIENCE:
- Massive contact database with sophisticated targeting capabilities
- Technology-driven approach that optimizes campaigns in real-time
- Multichannel coordination that keeps prospects engaged across touchpoints
- Strong track record with enterprise and complex B2B sales cycles
- Predictable processes designed for consistent results at scale
Operatix: Global Human-First Sales Acceleration
Operatix takes a different approach. Their 300+ strong team of SDRs specializes in helping B2B Software vendors accelerate growth by generating pipeline & revenue across North America, EMEA, LATAM & APAC. The emphasis here is on human expertise with global reach.
While their offices are located in the UK, US and Singapore, their services expand well beyond these locations. Covering over 20 languages, their multi-lingual team of native speakers can help you successfully tap into new markets, with strong comprehension of cultural differences and policies to overcome challenges unique to each country.
This isn’t just about having people who speak different languages. It’s about having SDRs who understand how business gets done in different regions. A cold call that works in Texas might completely fail in Germany, not because of language, but because of cultural expectations around business communication.
Operatix positions themselves as an extension of your sales team, not just a lead generation service. Their experienced sales representatives empower your sales engine, working as an extension of your current sales team to increase pipeline and accelerate growth. The integration is designed to be seamless.
The strength is cultural intelligence combined with sales expertise. When you’re expanding into new markets, having SDRs who understand local business practices, communication styles, and buyer behavior can be the difference between breaking into a region or failing expensively.
The potential challenge is coordination. Managing a global team across different time zones and cultural approaches requires sophisticated project management. The quality can vary depending on which region and which specific SDRs are assigned to your account.
Why companies choose Operatix:
- Global reach with native speakers across 20+ languages
- Deep cultural understanding for international market expansion
- Human-first approach with experienced sales representatives
- B2B software specialization with proven industry knowledge
- Seamless integration as an extension of existing sales teams
Head-to-Head: CIENCE vs Operatix in the Real World
This comparison really comes down to technology sophistication versus human cultural intelligence.
CIENCE excels when your prospects expect polished, data-driven outreach across multiple channels. Their machine-powered approach means consistent messaging, optimized timing, and systematic follow-up. If you’re selling to enterprise buyers who appreciate thoroughness and sophisticated sales processes, CIENCE’s approach resonates.
Operatix shines when relationships and cultural nuance matter more than technological sophistication. Their human-first approach means adaptable conversations, cultural sensitivity, and genuine relationship building. If you’re expanding globally or selling to markets where trust and personal connection drive decisions, Operatix has the advantage.
Pricing reality: CIENCE clients generally quote paying anywhere from around $4,200 to nearly $9,000 a month for sales development services. Operatix pricing isn’t publicly disclosed, but industry standards for global multilingual SDR services typically range in similar territory.
Both are premium services with premium pricing. The question isn’t which is cheaper, but which approach delivers better ROI for your specific market and sales process.
The Cold Calling Reality Check
Here’s what neither CIENCE nor Operatix addresses directly: the power of focused, high-quality cold calling.
Both companies excel at multichannel orchestration. CIENCE coordinates emails, LinkedIn, and calls through sophisticated sequences. Operatix blends human relationship building across multiple touchpoints and cultures. But in both cases, cold calling is one tactic among many, not the primary driver.
The challenge with multichannel approaches is dilution. When calls are just one touch in a complex sequence, they often become check-the-box activities rather than relationship-building conversations. SDRs focus on completing the sequence rather than maximizing the impact of each individual call.
Pure cold calling, done well, is still the fastest way to test messaging, handle objections in real-time, and build genuine rapport with prospects. It’s the only channel where you can hear hesitation in someone’s voice, adjust your pitch on the spot, and walk away with a qualified meeting in a single interaction.
Neither CIENCE nor Operatix is purely phone-first. For companies that want cold calling to be the core engine driving pipeline, a different approach is needed.
A Sharper Alternative: RemoteAides
This is where RemoteAides creates a distinct advantage. While CIENCE and Operatix split focus across multiple channels and complex global operations, RemoteAides is laser-focused on what works: professional, high-impact cold calling.
There’s no complicated multichannel orchestration. No global coordination challenges. Just experienced, English-fluent cold callers who understand your market, represent your brand professionally, and focus entirely on getting you qualified meetings through phone conversations.
The team consists of carefully selected African-based representatives who bring natural warmth to conversations, adapt quickly to different industries, and maintain the stamina needed for consistent high-volume calling. Every rep is handpicked for your specific market and trained on your unique value proposition.
What sets RemoteAides apart is the combination of focus and transparency. You’re not paying for sophisticated software platforms or global infrastructure. You’re paying for skilled cold callers who wake up every day with one goal: getting your prospects on the phone and booking qualified meetings.
Onboarding happens in days, not weeks. Pricing is transparent at €800 per month per rep with no hidden fees or complex contract terms. For founders who want a direct path from cold calling to pipeline without the complexity, RemoteAides delivers exactly that.
The Bottom Line
CIENCE delivers sophisticated, technology-powered multichannel campaigns for companies that value systematic processes and data-driven optimization. Operatix provides global sales acceleration with human cultural intelligence for companies expanding internationally.
Both are premium services with proven track records in their respective approaches.
But if your priority is simple, effective cold calling that generates meetings without the complexity and cost of multichannel orchestration, RemoteAides offers a more direct path to results.
The choice ultimately depends on whether you want technological sophistication, global cultural expertise, or focused cold calling excellence. Each approach works, but for different reasons and different types of companies.
FAQs
1. Which is better for cold calling specifically – CIENCE or Operatix? Both include cold calling as part of broader multichannel strategies. CIENCE coordinates calls within technology-optimized sequences. Operatix emphasizes human relationship building across cultures. Neither is purely phone-first.
2. How quickly can they start generating results? CIENCE typically requires several weeks for campaign setup and optimization. Operatix needs time for cultural alignment and global team coordination. Both prioritize setup thoroughness over speed to results.
3. What if I just want focused cold calling without multichannel complexity? RemoteAides specializes in pure cold calling excellence with transparent pricing and fast onboarding, eliminating the complexity of multichannel coordination while maximizing phone-first results.
4. How do pricing models compare? CIENCE ranges from $4,200 to $9,000+ monthly depending on scope. Operatix pricing varies by global requirements. RemoteAides offers transparent €800 per rep monthly with no hidden costs.
5. Which approach generates better ROI? ROI depends on your market, sales cycle, and prospect preferences. Multichannel sophistication works for complex enterprise sales. Focused cold calling often delivers faster results for straightforward B2B sales cycles.
